Every ingredient in the Complete Oral Care system, with the published research
behind it. Each study links straight to the journal it appeared in, so you can
read it in full for yourself.
Dr Weston A. Price
1870 – 1948
Where All of This Begins
The Wisdom Came First. The Science Caught Up.
In the 1930s a Cleveland dentist went looking for the healthiest mouths on
earth. He found them — and what they had in common wasn't dentistry.
It was dinner.
What he came back with
The old diet, unbroken. Broad arches. Teeth in straight rows.
A lifetime on the same food. Older adults, still with their
own teeth — the outcome Price kept finding wherever people were fed real,
nutrient-rich food.
01
Ancestral Wisdom
Thousands of years
Swiss villagers. Gaelic fishermen. Maasai herders. Inuit hunters. No contact,
no shared language, no common ancestry — and the same priorities at every
table: organ meats, oily fish, butter from grazing herds. They fed these foods
to mothers before conception and to children as their adult teeth came in. They
called them sacred. Nobody could say why.
02
What Price Documented
The 1930s
He set out to explain it. Ten years, fourteen societies, roughly fifteen thousand
photographs. Communities eating the traditional foods of their ancestors kept
strong, straight teeth; when refined flour and sugar arrived by supply ship, the
same families lost that protection within a single generation. Price traced it to
what he called the fat-soluble activators — the concentrated nutrients in
animal foods that the modern diet had stripped away.
03
What Modern Research Shows
Today
We can now measure what Price could only observe, and the nutrients keep pointing
back to the same foods. Vitamin D helps the body use the calcium teeth are built
from. Vitamin K2 helps direct that calcium into bone and teeth rather than soft
tissue. Vitamin A guides the formation of enamel itself. Every study on the rest of
this page puts modern evidence behind one of these nutrients — and the studies looked at individual nutrients
and ingredients, not Dentite Complete Care products.
The primary record
We're not asking you to take our word for any of this. Price's own work is here,
free to read in full.
1939Price WA · Paul B. Hoeber, New York · Full text free to read
Fourteen societies, roughly 15,000 photographs, dental examinations and food
analyses. Price observed that groups eating their traditional diets had markedly
better teeth — and that this changed when refined flour and sugar arrived.
1932Price WA · Journal of the American Dental Association · 19:1339 · Reproduced in Chapter 22
Price's own peer-reviewed dental publication on the fat-soluble activators — his
attempt to name the nutrients he'd watched protect people's teeth in the field.
Read Chapter 22
Dentite Tooth Armor · Outside-In
Nano-Hydroxyapatite
Tooth enamel is mostly hydroxyapatite. Nano-hydroxyapatite is the same mineral,
milled to a particle size close to enamel's own crystals. This is the most heavily
studied ingredient in the Dentite system — with human trials running as long as
eighteen months, and a European Commission safety assessment behind it.
2021Amaechi BT, Lemke KC, Saha S, Luong MN, Gelfond J · BDJ Open · 7:23
Double-blind trial at UT Health San Antonio. Over eight weeks, toothpaste
with 15% nano-hydroxyapatite relieved cold and air sensitivity as effectively
as a leading desensitising dentifrice.
2023Frontiers in Public Health · 11:1199728 · Open access
189 adults over eighteen months. 89.3% of the hydroxyapatite group showed no
increase in decayed, missing or filled surfaces, against 87.4% of the fluoride
group — an ingredient study, not a Dentite study.
2021Paszynska E et al. · Scientific Reports · Open access
207 children followed for 336 days, comparing a fluoride-free hydroxyapatite
toothpaste against a fluoride one. Caries occurrence was near-identical
between the two groups.
2019Schlagenhauf U et al. · 6-month controlled trial · NCT02705456
Braces are one of the hardest tests in oral care. In highly caries-active
patients, the hydroxyapatite dentifrice performed no differently from a
1400 ppm fluoride toothpaste.
A pre-registered synthesis of the fluoride-free nano-hydroxyapatite literature,
assessing whether it enhances remineralisation or slows demineralisation of
enamel.
2020Martins CC et al. · Journal of Dental Research · 99:514–522
Published in the field's leading journal, this network meta-analysis compares
every major desensitising agent against each other rather than one at a time.
2015Amaechi BT, Mathews SM, Ramalingam K, Mensinkai PK · American Journal of Dentistry · 28:33–39
Human root specimens worn in real mouths. Nano-hydroxyapatite formed a mineral
layer over dentin and formed a layer over exposed dentin — in a lab model.
2012Hannig M, Hannig C · Advances in Dental Research · 24:53–57
The mechanism paper. Nano-hydroxyapatite is thought to act as a calcium and
phosphate reservoir, holding the tooth surface in a supersaturated state that
favours crystal growth.
2025European Commission · Scientific Committee on Consumer Safety · SCCS/1677/25
The EU's consumer safety committee assessed nano-hydroxyapatite as safe at up to
29.5% in toothpaste and 10% in mouthwash — raising its own earlier limits after
a fresh review of the evidence.
2026Fandrich P, Stammler FJ, Enax J, Schulze zur Wiesche E, Amaechi BT, Fabritius H-O, Hellweg T · BDJ Open · 12:25 · Open access
Hydroxyapatite neutralised 98–99.9% of the acid in every solution tested,
including Coca-Cola and Sprite — most of it within 20 seconds, about the time
you'd swish a mouthwash. It releases calcium as it works, and its own structure
comes through intact.
View source
Dentite Tooth Armor · Outside-In
Theobromine
The alkaloid that gives cacao its bitterness. Lab and small clinical studies have looked at its effects on enamel.
2013Amaechi BT, Porteous N, Ramalingam K et al. · Caries Research · 47(5):399–405
The anchor study. Measured by surface microhardness and microradiography,
theobromine produced significant remineralisation — and was statistically
indistinguishable from a sodium fluoride toothpaste.
Volunteers wore dentin blocks on intraoral appliances for seven days.
Theobromine toothpastes occluded tubules faster than a bioglass comparator,
examined under scanning electron microscopy.
2021Durhan MA, Bilsel SO, Gokkaya B, Kulan Yildiz P, Kargul B · Acta Stomatologica Croatica · 55(1):18–27
One of the few clinical studies of theobromine in children, tracking salivary
pH, buffering capacity and Streptococcus mutans against a fluoride toothpaste.
2021Farhad F, Kazemi S, Bijani A, Pasdar N · Frontiers in Dentistry · Open access
Ninety extracted premolars, theobromine against 0.05% sodium fluoride, assessed
by microhardness and elemental spectroscopy.
View source
Dentite Tooth Armor · Outside-In
Nano Silver
Silver has a long history of use. At nanoscale its surface area
rises sharply, and so does its activity — which is why it now appears across modern
dentistry, from restorative materials to mouthwashes.
2004Sondi I, Salopek-Sondi B · Journal of Colloid and Interface Science · 275(1):177–182
The foundational paper, cited thousands of times since. Electron microscopy
showed silver nanoparticles accumulating in the bacterial membrane and pitting
the cell wall.
2015Corrêa JM et al. · International Journal of Biomaterials · Open access
A review of antimicrobial potential, mechanical properties, cytotoxicity and
long-term effectiveness — including the authors' call for more work on optimal
concentration.
2023Open access · Restorative, prosthetic, endodontic, implant and periodontal uses
A wide survey of where silver nanoparticles are used across dentistry, and where
the evidence is still thin.
View source
Gumtite Ozonated Oil Pulling · Outside-In
Ozonated Oil & Oil Pulling
Oil pulling is an ancient practice; ozonated oil is a modern upgrade to it. Research on it has focused mostly on the gumline — the places brushing tends to miss.
2025Frontiers in Oral Health · 12 randomised trials · 456 subjects · Open access
A review of olive oil studies (Gumtite does not contain olive oil). Assessed probing depth, bleeding
on probing and attachment level for periodontitis, and plaque, gingival and
bleeding indices for gingivitis.
2024Jong DO et al. · International Journal of Dental Hygiene · 25 trials · 1,184 participants
The most rigorous look at oil pulling to date: 25 trials and 1,184 participants.
The authors concluded there is a probable benefit for gingival health.
2025BMC Oral Health · 25:433 · Trials from 2018–2024 · Open access
A recent synthesis of ozone use in dental practice.
View source
Emu Oil & Nourish · Inside-Out
Vitamin D3, Vitamin K2 & Omega-3
The fat-soluble side of the ritual. These are the nutrients your body uses to place
minerals where they belong — the part of oral
health that no toothpaste can reach.
2013Hujoel PP · Nutrition Reviews · 71(2):88–97 · University of Washington
24 controlled trials across 2,827 children from the University of Washington's
Dr Philippe Hujoel. The review pooled trials of vitamin D and dental caries in children.
2023Li Z, Wei X, Shao Z, Liu H, Bai S · BMC Oral Health · 23:768 · Open access
13 studies of high methodological quality. Children with vitamin D deficiency
carried a 22% higher risk of dental caries than those with normal levels.
2013Knapen MH, Drummen NE, Smit E, Vermeer C, Theuwissen E · Osteoporosis International · 24:2499–2507
Three years of vitamin K2 as MK-7. Vitamin K activates osteocalcin, the protein
that binds calcium into bone — the same mineral chemistry your teeth depend on.
2023BMC Oral Health · 40 patients · Stage III–IV periodontitis · Open access
EPA and DHA alongside professional cleaning produced short-term benefits, most
clearly in the deeper pockets.
View source
Nourish · Inside-Out
Organ Nutrition
Traditional cultures ate the whole animal, and organs were the prized part. We're
not asking you to take that on faith. Below is the modern research on the specific
compounds organ meats concentrate — CoQ10, B12, folate, retinol and the trace
minerals — and what they do for teeth and gums.
2018Dommisch H, Kuzmanova D, Jönsson D, Grant M, Chapple I · Periodontology 2000 · 78(1):129–153
The cornerstone reference, in the field's most authoritative review journal. It
covers vitamin A, the B complex, C, D, E and coenzyme Q10, plus calcium,
magnesium, iron, zinc, copper, manganese and selenium — nearly every compound an
organ blend delivers.
2025Ten randomised trials · PROSPERO CRD42022311286 · Databases screened to May 2024
Beef heart is the richest dietary source of CoQ10. This review looked at CoQ10 supplements used
alongside professional dental care — it did not test
Nourish.
CoQ10 works as an antioxidant, scavenging the reactive oxygen species that drive
gum tissue breakdown. Gingival CoQ10 levels are known to fall in periodontitis.
2009Volkov I, Rudoy I, Freud T et al. · Journal of the American Board of Family Medicine · 22(1):9–16
Six months, placebo-controlled. Duration, ulcer count and pain all fell
significantly — and, interestingly, regardless of whether the person started
deficient.
1984Pack AR · Journal of Clinical Periodontology · 11(9):619–628
Sixty subjects, four weeks, double-blind. Folate produced significant reductions
in gum redness and bleeding — early evidence that this B vitamin matters to
the health of gum tissue.
2023Samuel SR, Lai CWM, Khan MM, Mathew MG, Kramer MS, Hsu CYS · Journal of Dental Research
Vitamin A is central to how enamel forms in the first place, and liver is the
richest food source of it. Vitamin A has a daily upper limit, so speak to your
healthcare provider before adding liver if you're pregnant.
2023Kuzmanova D, Dommisch H · European Federation of Periodontology
From Europe's periodontal authority: people with periodontitis show significantly
lower dietary intake of calcium, magnesium, copper and selenium — with matching
lower serum and saliva levels.
View source
Support Your Smile From Both Directions
Enamel support, ozonated oil pulling, and fat-soluble nutrition — the
complete outside-in and inside-out ritual, with the ingredient research on this page for background.
The research on this page is provided for information only. These statements have not
been evaluated by the Food and Drug Administration. Dentite Complete Care products are
not intended to diagnose, treat, cure or prevent any disease. Studies referenced
examined individual ingredients or compounds, not Dentite Complete Care products. Oral
health is personal — please consult a dental or healthcare professional about your own
circumstances.
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